Cardiac Biomechanics Lab »  People »  Principal Investigators »  Mark Ratcliffe, M.D.
Mark Ratcliffe, M.D.

Mark Ratcliffe, M.D.

Professor of Surgery
Division of Adult Cardiothoracic Surgery, UCSF
Co-Director, Cardiac Biomechanics Lab

Contact Information

4150 Clement Street
San Francisco, CA  94121
Tel: 415-750-2057
Fax: 415-750-2181
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  • M.D.-Case Western Reserve University, Cleveland, OH
  • B.A. - Denison University, Granville, OH
  • Internship - John Hopkins Hospital, Baltimore, MD
  • Residency - John Hopkins Hospital, Baltimore, MD
  • Residency - University of Pennsylvania Hospital, Philadelphia, PA
  • Research Fellow - University of Pennsylvania Hospital, Philadelphia, PA
  • Fellowship - University of Pennsylvania Hospital, Philadelphia, PA
  • American Board of Surgery, 1989
  • American Board of Thoracic Surgery, 1993
  • Minimally invasive cardiac surgery
  • Off-pump coronary artery bypass surgery
  • Robotic surgery
  • Surgery for heart failure
  • Thoracic aortic surgery
  • Valve repair and replacement
  • Finite element analysis of failing left ventricle

Dr. Ratcliffe received his M.D. degree from Case Western Reserve School of Medicine and completed his General Surgery and Cardiothoracic residencies at the Univeristy of Pennsylvania. Dr. Ratcliffe is certified by the American Board of Surgery and American Board of Thoracic Surgery. His special interest is in the application of finite element analysis or the failing left ventricle. Dr. Ratcliffe has been on the faculty since 1993. Currently, he is Director of the Cardiac Biomechanics Laboratory.

Dr. Ratcliffe is an active member of the American Society for Artificial Internal Organs, American Heart Association, Society of Thoracic Surgeons, Western Thoracic Surgical Association, San Francisco Surgical Society, American Association of Thoracic Surgery, and is a Fellow of the American College of Surgeons.

Most recent publications from a total of 102
  1. Kim J, Rodriguez-Diego S, Srinivasan A, Brown RM, Pollie MP, Di Franco A, Goldburg SR, Siden JY, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW. Echocardiography-quantified myocardial strain-a marker of global and regional infarct size that stratifies likelihood of left ventricular thrombus. Echocardiography. 2017 Aug 22. View in PubMed
  2. Kim J, Di Franco A, Seoane T, Srinivasan A, Kampaktsis PN, Geevarghese A, Goldburg SR, Khan SA, Szulc M, Ratcliffe MB, Levine RA, Morgan AE, Maddula P, Rozenstrauch M, Shah T, Devereux RB, Weinsaft JW. Right Ventricular Dysfunction Impairs Effort Tolerance Independent of Left Ventricular Function Among Patients Undergoing Exercise Stress Myocardial Perfusion Imaging. Circ Cardiovasc Imaging. 2016 Nov; 9(11). View in PubMed
  3. Pantoja JL, Morgan AE, Grossi EA, Jensen MO, Weinsaft JW, Levine RA, Ge L, Ratcliffe MB. Undersized Mitral Annuloplasty Increases Strain in the Proximal Lateral Left Ventricular Wall. Ann Thorac Surg. 2016 Oct 5. View in PubMed
  4. Morgan AE, Wozniak CJ, Gulati S, Ge L, Grossi EA, Weinsaft JW, Ratcliffe MB. Association of Uneven MitraClip Application and Leaflet Stress in a Finite Element Model. JAMA Surg. 2016 Oct 5. View in PubMed
  5. Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE. Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model. J Heart Valve Dis. 2016 Jul; 25(4):424-429. View in PubMed
  6. Ge L, Wu Y, Soleimani M, Khazalpour M, Takaba K, Tartibi M, Zhang Z, Acevedo-Bolton G, Saloner DA, Wallace AW, Mishra R, Grossi EA, Guccione JM, Ratcliffe MB. Moderate Ischemic Mitral Regurgitation After Posterolateral Myocardial Infarction in Sheep Alters Left Ventricular Shear but Not Normal Strain in the Infarct and Infarct Borderzone. Ann Thorac Surg. 2016 May; 101(5):1691-9. View in PubMed
  7. Morgan AE, Pantoja JL, Weinsaft J, Grossi E, Guccione JM, Ge L, Ratcliffe M. Finite Element Modeling of Mitral Valve Repair. J Biomech Eng. 2016 Feb 1; 138(2). View in PubMed
  8. Goyal P, Kim J, Feher A, Ma CL, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW. Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention. Coron Artery Dis. 2015 Dec; 26(8):642-50. View in PubMed
  9. Pantoja JL, Zhang Z, Tartibi M, Sun K, Macmillan W, Guccione JM, Ge L, Ratcliffe MB. Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis. Ann Thorac Surg. 2015 Dec; 100(6):2198-205. View in PubMed
  10. Yaffee DW, Grossi EA, Ratcliffe MB. Progressive design concepts in off-pump left ventricular remodeling mitral valve repair devices. Ann Cardiothorac Surg. 2015 Jul; 4(4):352-4. View in PubMed
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